Funding for this research was provided by:
Academicians and Experts Workstation of Yunnan Province (202005AF150033)
Beijing Hospital Clinical Research 121 Project (BJ-2018-204)
National Natural Science Foundation of China (81302277)
Yunnan Provincial Science and Technology Department (202001AY070001-128)
Received: 29 April 2021
Accepted: 27 January 2022
First Online: 9 February 2022
: The PROSPECT trial received approval from the Beijing Hospital Ethics Committee and is registered on the Chinese Clinical Trial Registry (ChiCTR2100021719). All participants will give verbal and written informed consent.
: Written consent will be obtained from all participants to use anonymized quotes for reporting and publication purposes.
: The authors declare that they have no competing interests.