Funding for this research was provided by:
the Shandong Clinical Medical Research Center for Cardiovascular and Cerebrovascular Diseases of Traditional Chinese Medicine
National Natural Science Foundation of China (81774242, 81774173)
Shandong Province Health Science and Technology Development Plan of 2020 (202003011161)
Shandong Province Traditional Chinese Medicine Science and Technology Development Program (2015-100)
Received: 17 February 2021
Accepted: 7 February 2022
First Online: 22 February 2022
: The protocol (version 2.0, dated 10 January 2020) was approved by the clinical research ethics committee of the Affiliated Hospital of Shandong University of TCM (approval (2019)伦审(064)号-KY). It has been registered with the Chinese Clinical Trial Registry (ChiCTR2000030611). The trial complies with the principles of the Declaration of Helsinki and the principles of good clinical practice. Each participant must sign the clinical trial consent form before enrollment, and they have the right to withdraw from the trial at any time.
: We obtained informed consent for publication of the dataset from the participant at the point of recruitment to the trial. All participants will be completely anonymous.
: The authors declare no conflict of interest.