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Identifying disrupted biological factors and patient-tailored interventions for chronic fatigue in adolescents and young adults with Q-Fever Fatigue Syndrome, Chronic Fatigue Syndrome and Juvenile Idiopathic Arthritis (QFS-study): study protocol for a randomized controlled trial with single-subject experimental case series design

Crossref DOI link: https://doi.org/10.1186/s13063-022-06620-2

Published Online: 2022-08-19

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Vroegindeweij, Anouk http://orcid.org/0000-0002-7769-5459
Swart, Joost F.

Houtveen, Jan

Eijkelkamp, Niels

van de Putte, Elise M.

Wulffraat, Nico M.

Nijhof, Sanne L.
Funding

Funding for this research was provided by:

ZonMw (50-53000-98-566)
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Text and Data Mining valid from 2022-08-19

Version of Record valid from 2022-08-19
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Article History

Received: 7 June 2022

Accepted: 2 August 2022

First Online: 19 August 2022

Declarations

:

: The UMC Utrecht IRB reviewed and approved the QFS-study protocol titled “A study focused at identifying disrupted biological factors and patient-tailored interventions for adolescents with Q-fever fatigue syndrome” on June 16, 2020. IRB’s reference number: 20/166. Participants and their parents receive verbal and written information about the study and informed consent will be obtained from all participants before randomization. In case participants are under the age of 16, informed consent will be obtained from the participant and his/her parents or legal guardians.

: It is possible to receive a model consent form from the corresponding author upon request.

: The authors declare that they have no competing interests.

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