Bergholz, Alina
Meidert, Agnes S.
Flick, Moritz
Krause, Linda
Vettorazzi, Eik
Zapf, Antonia
Brunkhorst, Frank M.
Meybohm, Patrick
Zacharowski, Kai
Zarbock, Alexander
Sessler, Daniel I.
Kouz, Karim
Saugel, Bernd
Funding for this research was provided by:
Deutsche Forschungsgemeinschaft (445158321)
Universitätsklinikum Hamburg-Eppendorf (UKE)
Article History
Received: 27 September 2022
Accepted: 19 October 2022
First Online: 17 November 2022
Change Date: 10 February 2023
Change Type: Update
Change Details: Missing Open Access funding information has been added in the Funding Note.
Declarations
:
: Ethics committee approval is obtained for each site prior to patient documentation. All participating patients need to provide written informed consent (obtained by dedicated trial personnel) before trial inclusion.
: Not applicable.
: AB, ASM, LK, EV, AZap, FMB, PM, and AZar declare that they have no competing interests. MF has received institutional restricted research grants and honoraria for giving lectures and consulting from CNSystems Medizintechnik GmbH (Graz, Austria). MF is a consultant for Edwards Lifesciences Inc. (Irvine, CA, USA). The Department of Anaesthesiology, Intensive Care Medicine & Pain Therapy of the University Hospital Frankfurt, Goethe University, received support from B. Braun Melsungen, CSL Behring, Fresenius Kabi, and Vifor Pharma for the implementation of Frankfurt’s Patient Blood Management program. KZ has received honoraria for participation in advisory board meetings for Haemonetics and Vifor and received speaker fees from CSL Behring, Masimo, Pharmacosmos, Boston Scientific, Salus, iSEP, Edwards, and GE Healthcare. He is the principal investigator of the EU-Horizon 2020 project ENVISION (intelligent plug-and-play digital tool for real-time surveillance of COVID-19 patients and smart decision-making in intensive care units) and Horizon Europe 2021 project COVend (biomarker and AI-supported FX06 therapy to prevent progression from mild and moderate to severe stages of COVID-19). DIS is a consultant for Edwards Lifesciences (Irvine, CA, USA) and has received research funding from the company. He has equity interests in Sensifree (Cupertino, CA, USA) and Perceptive Medical (Newport Beach, CA, USA). KK is a consultant for Edwards Lifesciences Inc. (Irvine, CA, USA) and for Vygon (Aachen, Germany). BS is a consultant for and has received institutional restricted research grants and honoraria for giving lectures from Edwards Lifesciences Inc. (Irvine, CA, USA). BS is a consultant for and has received institutional restricted research grants and honoraria for giving lectures from Pulsion Medical Systems SE (Feldkirchen, Germany). BS has received honoraria for giving lectures from Getinge AB (Gothenburg, Sweden). BS has received institutional restricted research grants and honoraria for giving lectures from CNSystems Medizintechnik GmbH (Graz, Austria). BS is a consultant for and has received honoraria for giving lectures from Philips Medizin Systeme Böblingen GmbH (Böblingen, Germany). BS is a consultant for and has received institutional restricted research grants and honoraria for giving lectures from GE Healthcare (Chicago, IL, USA). BS is a consultant for and has received honoraria for giving lectures from Vygon (Aachen, Germany). BS is a consultant for and has received honoraria for giving lectures from Baxter (Deerfield, IL, USA). BS is a consultant for and has received institutional-restricted research grants from Retia Medical LLC (Valhalla, NY, USA). BS has received institutional restricted research grants from Osypka Medical (Berlin, Germany). BS was a consultant for and has received institutional restricted research grants from Tensys Medical Inc. (San Diego, CA, USA).