Funding for this research was provided by:
National Institutes of Health (R01-AG035083, P01-AG003991, R01-NS085419, R01-AG044546, K01AG046374)
National Institute on Aging (U19AG032438, P50-AG05681, P01-AG026276, RF1AG053303, P01-AG03991)
Alzheimer's Association (NIRG-11-200110)
BrightFocus Foundation (A2013359S)
Brain and Behavior Research Foundation (R01NS102272)
Received: 5 March 2018
Accepted: 15 May 2018
First Online: 8 June 2018
Ethics approval and consent to participate
: All research participants contributing clinical, genetic, or tissue samples for genetic analysis to this study provided written informed consent, subject to oversight by the Washington University in St. Louis, Mayo clinic or Mount Sinai School of Medicine review boards. All procedures of the Knight-ADRC (201105102) and DIAN (201106339) studies were approved by the Washington University Human Research Protection Office and written informed consent was obtained from each participant. The study was conducted according to the principles of the Declaration of Helsinki. All animal procedures were performed in accordance with the guidelines of Washington University’s Institutional Animal Care and Use Committee.
: The authors declare that they have no competing interests.
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