Funding for this research was provided by:
National Institutes of Health (R01HL131573)
Canadian Institutes of Health Research
Received: 10 March 2020
Accepted: 4 September 2020
First Online: 28 September 2020
Ethics approval and consent to participate
: The Atherosclerosis Risk in Communities (ARIC) study, Cardiovascular Health Study (CHS), and Framingham Heart Study (FHS) have been approved by the Institutional Review Board (IRB) at each participating institution. All participants provided written informed consent.The ARIC study design and methods were approved by four different IRBs at each of the collaborating medical institutions: University of Mississippi Medical Center Institutional Review Board (Jackson Field Center); Wake Forest University Health Sciences Institutional Review Board (Forsyth County Field Center); University of Minnesota Institutional Review Board (Minnesota Field Center); and Johns Hopkins University School of Public Health Institutional Review Board (Washington County Field Center).FHS is approved by the IRB at Boston University Medical Center. CHS recruited participants from Medicare lists at four sites and IRBs at each site were involved in human subject approval.This research conforms to the principles of the Helsinki Declaration.
: Not applicable.
: The authors declare that they have no competing interests.