Funding for this research was provided by:
National Medical Research Council (NMRC/CSSSP/0003/2016, NMRC/CG/M006/2017_NHCS, NMRC/STaR/0026/2015, NMRC/STaR/0011/2012)
Industry Alignment Funds Pre-Positioning (H17/01/a0/007)
, SingHealth Duke-NUS Academic Clinical Programme
Received: 4 June 2020
Accepted: 7 December 2020
First Online: 7 January 2021
Ethics approval and consent to participate
: Ethics approval was obtained by the SingHealth Central Institutional Review Board (Reference No.: 2013/605/C) to collect participant genetic and phenotypic data in 2014. Approval was amended to include the collection of family history in October 2016. Informed consent to participate was obtained from participants for this study. All experiments were performed in accordance with relevant guidelines and regulations. This research conforms to the principles of the Helsinki Declaration.
: Informed consent was collected from all subjects to publish de-identified data.
: The authors declare that they have no competing interests.