Funding for this research was provided by:
National Institutes of Health (RO1 DK067536, UC4 DK 116278, RO1 DK117639, RO1 DK105588)
Joslin Diabetes Center (P30 DK 36836)
Received: 17 July 2020
Accepted: 13 July 2021
First Online: 10 August 2021
: Ethical approval for the usage of human islets was granted by the Ethics Committee of the Joslin Diabetes Center for Human Studies (#05-05). The study complied with all relevant ethical regulations for work with human cells for research purposes. Written informed consent for participation was not required for this study in accordance with the national legislation and the institutional requirements. The human islets that are distributed by the IIDP are from approved cadaveric organ donors from which at least one other organ has been approved for transplantation. Because the donors are brain dead, the IRB’s from the institutions that isolate the islets consider the tissue as “Exempt” from Human Studies Approval.Animal studies and protocols were approved by the Institutional Animal Care and Use Committees of the Joslin Diabetes Center (IACUC #05-01, #2012-09). Animal studies and protocols were approved by the Institutional Animal Care and Use Committees of the Joslin Diabetes Center (IACUC #05-01, #2012-09).All research performed in this study followed the Declaration of the Helsinki Ethical Principles for Medical Research Involving Human Samples.
: Not applicable.
: The authors declare that they have no competing interests.