Funding for this research was provided by:
Medical Research Council (MR/T001151/1)
National Institute for Health Research (NIHR200915)
Wellcome Trust (203141/Z/16/Z)
Received: 22 January 2021
Accepted: 3 August 2021
First Online: 3 September 2021
: The Infections in Oxfordshire Research Database (IORD; ExternalRef removed) has generic Research Ethics Committee, Health Research Authority and Confidentiality Advisory Group approvals ( 19/SC/0403, 19/CAG/0144) which facilitate the pseudo-anonymised linkage of routinely collected NHS electronic healthcare record data from the Oxford University Hospitals NHS Foundation Trust Clinical Systems Data Warehouse and research data (e.g. sequencing data) from the Antimicrobial Resistance and Modernising Microbiology Theme of the Oxford NIHR Biomedical Research Centre, Oxford. IORD links records by a specific, random, number ensuring that no patient-identifiable information is shared with researchers using this resource. We sequenced bacterial isolates from bloodstream infections that are routinely stored by the John Radcliffe Hospital Microbiology laboratory. In the UK, bacterial isolates (such as those sequenced in this study) routinely cultured from human clinical samples do not require ethical approval for analysis under the provisions of the Human Tissue Act as they do not contain any material considered to be human tissue.
: Not applicable
: The authors declare that they have no competing interests.