Funding for this research was provided by:
U.S. Department of Defense (PR120641)
Shenzhen science and technology research and development funds (JCYJ20160331173652555)
Shandong Provincial Natural Science Foundation, China (ZR2012HM038)
The Scleroderma Foundation, and the National Institutes of Health/National Institute of Arthritis and Musculoskeletal and Skin Diseases (T32AR007080)
Received: 4 May 2017
Accepted: 17 January 2018
First Online: 12 February 2018
: All experiments performed with animals were done with the approval from the University of Michigan’s Institutional Animal Care and Use Committee (IACUC). IACUC protocol PRO00006340 was approved on June 16, 2015, and expires on June 16, 2018. The University of Michigan is accredited by the Association for Assessment and Accreditation of Laboratory Animal Care International, and the animal care and use program conforms to the National Institutes of Health standards set forth in the Guide for the Care and Use of Laboratory Animals (revised 2011). All experiments involving human subjects were done with the approval of the University of Michigan Institutional Review Board (IRBMED). IRBMED protocol HUM00089350 was approved on March 1, 2017, and expires on February 28, 2018. Written informed consent was obtained from all subjects in the study.
: Not applicable.
: AEK is now an employee of Eli Lilly and Company. The other authors declare that they have no competing interests.
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