Text and Data Mining valid from 2018-08-03
Received: 11 April 2018
Accepted: 12 July 2018
First Online: 3 August 2018
Ethics approval and consent to participate
: The study was approved by the ethics committee of Kyoto University (approval number R0357) as well as the ethics committees of all six institutions (Osaka University, Osaka Medical College, Kansai Medical University, Kobe University, Nara Medical University, and Osaka Red Cross Hospital). The study was conducted in accordance with the Declaration of Helsinki and written informed consent was obtained from all participants.
: Not applicable.
: MH and MT are affiliated with a department that is financially supported by four pharmaceutical companies (Mitsubishi-Tanabe, Chugai, Ayumi, and UCB Japan) and the city government (Nagahama City). MH received a research grant from Astellas. AO received a research grant from Eisai, Asahi-Kasei Pharma, and Mitsubishi-Tanabe. TH received a research grant and/or speaker fee from Astellas, Chugai, Eisai, Mitsubishi Tanabe, Abbvie, and Asahi-Kasei. MT received research grants from Astellas, Abbvie, Pfizer, and Taishotoyama. HI received a research grant and/or speaker fee from Bristol-Myers, Astellas, Asahi-Kasei, and Eli Lily. TF received a research grant and/or speaker fee from Pfizer Japan Inc., Ono Pharmaceutical Co., Ltd, Daiichi Sankyo Co., Ltd, Mitsubishi-Tanabe Pharma Corporation, Eisai Co., Ltd, AbbVie GK, and Astellas Pharma Inc. KO received a research grant and/or speaker fee from Abbvie, Astellas, Bristol-Myers Squibb, Eli Lily, Mitsubishi-Tanabe, Pfizer, and Takeda. TM received research grants from Acterion, Astellas, Asahi Kasei Pharma, Ayumi, Chugai, Daiichi Sankyo, Eisai, JB, Mitsubishi Tanabe, MSD, Nippon Shinyaku, Pfizer, Sanofi, and Takeda, and has participated in speakers’ bureaus for Astellas, Bristol-Myers Squibb, Chugai, and Mitsubishi-Tanabe. The remaining authors have no financial conflicts of interest to disclose concerning this manuscript. The pharmaceutical companies had no role in the design of the study, the collection or analysis of the data, the writing of the manuscript, or the decision to submit the manuscript for publication.
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