Funding for this research was provided by:
Novartis Pharmaceuticals Corporation
Merck Sharp and Dohme
Received: 16 March 2018
Accepted: 19 September 2018
First Online: 10 October 2018
Ethics approval and consent to participate
: The study was conducted in accordance with the principles of the Declaration of Helsinki. Ethics approval for the study was obtained from Hospital Clinic (Barcelona, Spain). The institutional review board at each participating center approved the protocol.
: Not applicable.
: The authors declare that they have no competing interests.
: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.