Funding for this research was provided by:
National Natural Science Foundation of China (81788104, 81630044, 81601432, 81771763 and 91542000)
Chinese Academy of Medical Science Innovation Fund for Medical Sciences (CIFMS2017-12M-1-008, 2016-12M-1-003, 2017-I2M-3-011 and 2016-12M-1-008)
National Key Research and Development Program: “Precise Medical Research” (2016YFC0903900)
2016 PUMC Hospital Fund for Junior Faculty (pumch-2016-2.1)
Natural Science Foundation of Beijing, China (7182129)
Received: 27 January 2019
Accepted: 2 August 2019
First Online: 19 August 2019
Ethics approval and consent to participate
: The study protocol was approved by the Institutional Ethics Committee of PUMC Hospital (S-K 807).
: Not applicable.
: The authors declare that they have no competing interests.