Funding for this research was provided by:
the Japanese Ministry of Education, Global Center of Excellence (GCOE) Program, International Research Center for Molecular Science in Tooth and Bone Diseases
Takeda Science Foundation
Received: 19 April 2019
Accepted: 8 August 2019
First Online: 20 August 2019
: The experimental protocol for animal study was approved by the Institutional Animal Care and Use Committee of Tokyo Medical and Dental University. The experimental protocol for human study was approved by the Ethics Committee of the Tokyo Medical University, and all subjects provided informed consent according to the Declaration of Helsinki principles.
: Not applicable.
: The authors declare that they have no competing interests.