Funding for this research was provided by:
National Natural Science Foundation of China (81772401, U1603121)
Natural Science Foundation of Hubei Province (WJ2017Z016)
Received: 9 November 2018
Accepted: 23 August 2019
First Online: 3 September 2019
Ethics approval and consent to participate
: All human tissues were obtained and used with the informed consent of the patients and under the approval of the Ethics Committee of Tongji Medical College, Huazhong University of Science and Technology. The animal studies were approved by the Animal Experimentation Committee of Huazhong University of Science and Technology.
: All authors approved the final version of the manuscript to be published.
: The authors declare that they have no competing interests.