Received: 4 September 2019
Accepted: 25 November 2019
First Online: 30 December 2019
Ethics approval and consent to participate
: This study was approved by the research ethics committee of the Keio University School of Medicine (#20140335) and was conducted according to the Declaration of Helsinki.
: Informed consent was obtained from all patients and HCs.
: KM, KS, and KY declare that they have no competing interests. NS, HT, and KC were employees of Mitsubishi Tanabe Pharma Corporation. TT has received research grants from Mitsubishi Tanabe Pharma Corporation.