Received: 30 January 2020
Accepted: 11 August 2020
First Online: 9 September 2020
Ethics approval and consent to participate
: The medical ethics committee of the University Medical Center Utrecht had approved the study. All patients had provided written informed consent before entering the study.
: All authors had full access to the study data; contributed to data analysis, data interpretation, and writing and review of the manuscript; and approved the final version for publication.
: EHS is employee of Crescendo Bioscience, Inc. MS-K received a research grant from AstraZeneca. AstraZeneca was not involved in this study. MJHdH is an employee of Novartis Pharma BV. Novartis Pharma BV was not involved in this study. JWJB reported grants and fees from Roche, AbbvVie, Bristol-Myers, Squibb, Merck Sharp & Dohme, Pfizer, and UCB. FPJGL is co-founder, shareholder, and co-director of ArthroSave BV and is consultant for Synerkine Pharma BV. ArthroSave and Synerkine were not involved in this study. MSJ, JWGJ, JT, and PMJW report no competing interests.