Funding for this research was provided by:
Received: 5 November 2019
Accepted: 22 September 2020
First Online: 15 October 2020
Ethics approval and consent to participate
: Each randomized controlled trial was conducted in accordance with the Declaration of Helsinki and International Conference on Harmonization Guidelines for Good Clinical Practice and was approved by the institutional review board and/or independent ethics committee for each study center. All patients provided written informed consent.
: Not applicable.
: VS has received consulting fees or other remuneration from AbbVie, Amgen, Bristol-Myers Squibb, Corrona, Eli Lilly, Janssen, Novartis, Pfizer Inc, and UCB.JK has participated in speakers’ bureaus and has consulted for Pfizer Inc.RA has received research grants and speakers’ honoraria from Pfizer Inc.GW was an employee and shareholder of Pfizer Inc at the time of the analysis.AD, HS, RG, and CWM are employees of Pfizer Inc and own stock or stock options in Pfizer Inc.