Funding for this research was provided by:
Received: 15 January 2020
Accepted: 22 January 2020
First Online: 11 February 2020
Ethics approval and consent to participate
: The study protocol was approved by the Central Ethic Committee of the University Hospital of Liège in Belgium (namely Comité d’Ethique Hospitalo-Facultaire Universitaire de Liège). Agreement number: 707. This RCT was also registered on Clinical trial.gov on 13 September 2016 (NCT02909621).
: Not applicable
: YH is a consultant for Tilman SA and the founder and chairman of Artialis SA, a spin-off company of University of Liège developing biomarkers. All other authors declare that they have no competing interests.