Funding for this research was provided by:
Natural Science Foundation of China (82001709)
State Key Laboratory of Drug Research (SIMM2105KF-06)
National Natural Science Foundation of China (81771737)
Science and Technology Commission of Shanghai Municipality (19411970100)
Received: 23 July 2021
Accepted: 16 March 2022
First Online: 28 March 2022
: All participants gave their informed consent before entering the study. The study was approved by the ethics committee of Renji Hospital, Shanghai Jiao Tong University School of Medicine, and conducted in accordance with good clinical practice.
: All participants gave their informed consent to publication.
: N.S. has received research funds from EMD Serono (a business of Merck KGaA, Darmstadt, Germany). The other authors declare that they have no competing interests.