Funding for this research was provided by:
national natural science foundation of china (81770835)
guangzhou science and technology program project, china (201803040012)
the key-area research and development program of guangdong, china (2019B020230001)
basic and applied basic research foundation of guangdong province (2019A1515110658)
guangdong medical science and technology research foundation (20181031141744728)
Received: 4 July 2021
Accepted: 27 October 2021
First Online: 10 November 2021
: This research was approved by the Ethics Committee in Zhujiang Hospital of Southern Medical University, following the principle of Helsinki Declaration.
: The written informed consents for publication were acquired from each participant.
: All authors declared no competing interests.