Funding for this research was provided by:
Dunhill Medical Trust (R492/0516)
Received: 8 January 2020
Accepted: 13 March 2020
First Online: 24 March 2020
Ethics approval and consent to participate
: All volunteers gave their informed written consent in accordance with the Declaration of Helsinki and following approval from and in accordance with the South West Research Ethics Committee (16/SW/0099). This study was registered as a clinical trial (NCT02792621).
: Not applicable.
: The authors have declared that they have no competing interests.