Funding for this research was provided by:
National Institutes of Health (U01AI069907, U01AI069923, U01AI096299, U01AI069911, U01AI069924, U01AI069919)
Eunice Kennedy Shriver National Institute of Child Health and Human Development (R01 HD079214)
Received: 3 December 2019
Accepted: 3 May 2020
First Online: 24 May 2020
Ethics approval and consent to participate
: The IeDEA data analyzed in this manuscript were collected from over 300 sites in 35 countries. Each of the local sites and regional cohort data and coordinating centers has their own IRBs under which they are authorized to collect and analyze research data. These IRBs are all registered with the US Officer of Human Research Protections of the US Department of Health and Human Services, and local approval by these IRBs is required prior to receiving IeDEA funding. This work was also approved by the Partners Healthcare IRB (Boston, MA).
: Not applicable (no individual patient data are reported).
: The authors declare that they have no competing interests.