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High serum levels of reactive nitrogen species and low total antioxidant capacity in patients with resistant hypertension compared to those in age- gender matched healthy controls, controlled hypertension and follow up with propranolol treatment in the extended APPROPRIATE trial

Crossref DOI link: https://doi.org/10.1186/s13104-024-06884-8

Published Online: 2024-08-13

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Ranasinghe, H. N.

Weeratunga, P. N.

Fernando, N.

Katulanda, P.

Rajapakse, S.

Galappatthy, P.

Handunnetti, S. M.

Constantine, G. R.
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Article History

Received: 26 April 2024

Accepted: 1 August 2024

First Online: 13 August 2024

Declaration

:

: The study was approved by the Ethics Review Committee (ERC) of the Faculty of Medicine, University of Colombo (EC/15/152), (EC/21/002) and the Ethics Review Committee of National Hospital Sri Lanka. The trial was also registered at the Sri Lanka Clinical Trials Registry (SLCTR/2016/002). Date of Registration 27th Jan 2016, . Informed written consent was obtained from all subjects prior to recruitment to the study. Participants were recruited on voluntary basis and they could leave the study at any time they wished.

: The authors declare no competing interests.

: Not applicable.

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