Funding for this research was provided by:
National Institutes of Health (R01AI091905, R01AI121226)
Biotechnology and Biological Sciences Research Council (BB/I025263/1, BBI025751/1)
Medical Research Council (MC_UU_12013/8, MC_UU_12013/2, MC_UU_12013/1)
Text and Data Mining valid from 2019-12-01
Received: 17 April 2019
Accepted: 15 November 2019
First Online: 2 December 2019
Ethics approval and consent to participate
: The IOW cohort study was approved by Isle of Wight, Portsmouth and Hampshire Local Research Ethics Committee (06/Q1701/34).For ALSPAC, ethical approval for the study was obtained from the ALSPAC Ethics and Law Committee and the Local Research Ethics Committees and consent for collection of biological samples was provided in accordance with the Human Tissue Act (2004). For age seven years, United Bristol Healthcare Trust: E4168 (ALSPAC Hands on Assessments at Age Seven), Southmead Health Services: 67/98 (Avon Longitudinal Study of Pregnancy and Childhood (ALSPAC) - Hands on Assessments at Age Seven) and Frenchay Healthcare Trust: 98/52 (Avon Longitudinal Study of Pregnancy and Childhood (ALSPAC). Hands on Assessments at Age Seven). For age 15 years, Central & South Bristol Research Ethics Committee (UBHT): 06/Q2006/53 Avon Longitudinal Study of Parents and Children (ALSPAC), Hands on Assessments: Teen Focus 3 (Focus 15+), and for age 17 years, North Somerset & South Bristol Research Ethics Committee: 08/H0106/9 Avon Longitudinal Study of Parents and Children (ALSPAC), Hands on Assessments: Teen Focus 4 (Focus 17+). Full details of ethical approvals (local committees and approval numbers) are available at ExternalRef removed.
: Not applicable.
: The authors declare that they have no competing interests.