Funding for this research was provided by:
Alzheimer’s Research UK (ARUK-PG2017B-10)
Chief Scientist Office, Scottish Government Health and Social Care Directorate (Funding for Generation Scotland, Funding for the LBC1921)
Magnus Bergvalls Stiftelse
Age UK (Funding for the LBC1936)
Stiftelsen för Gamla Tjänarinnor
Medical Research Council (Precision Medicine Studentship, MR/M01311/1)
Wellcome (108890/Z/15/Z Translational Neuroscience Studentship, 104036/Z/14/Z)
College of Medicine and Veterinary Medicine, University of Edinburgh (Precision Medicine Studentship)
Scottish Funding Council (Founding for Generation Scotland)
Biotechnology and Biological Sciences Research Council (Funding for the LBC1921)
Loo och Hans Ostermans Stiftelse för Medicinsk Forskning
Received: 31 October 2019
Accepted: 9 March 2020
First Online: 26 March 2020
Ethics approval and consent to participate
: Generation Scotland has been ethically approved and granted research tissue bank status by the NHS East of Scotland Research Ethics Service(REC reference numbers: 05/S1401/89 and 15/ES/0040, respectively). Ethical approval for the first wave of Lothian Birth Cohort studies was obtained from the Multi-Centre Research Ethics Committee for Scotland (MREC/01/0/56) and the Lothian Research Ethics committee (LREC/1998/4/183; LREC/2003/2/29). All participants provided written informed consent.
: Not applicable.
: AMM has received research support from Eli Lilly, Janssen and the Sackler Trust. AMM has also received speaker fees from Janssen and Illumina. The other authors declare that they have no competing interests.