Funding for this research was provided by:
National Center for Child Health and Development (2019B4, 28-6)
Japan Agency for Medical Research and Development (20ek0109373h0003)
Takeda Science Foundation
Foundation for Growth Science
Received: 8 March 2020
Accepted: 14 May 2020
First Online: 16 June 2020
Ethics approval and consent to participate
: This study was approved by the Institutional Review Board Committee at the National Center for Child Health and Development (committee’s reference number: 518) and performed after obtaining written informed consent to participate in this study from the patients or the patients’ parents.
: We obtained written informed consent from the patients or the patients’ parents to publish patients’ clinical and molecular information as well as facial photographs.
: The authors declare that they have no competing interests.