Funding for this research was provided by:
Chief Scientist Office, Scottish Government Health and Social Care Directorate
Scottish Funding Council
Brain and Behavior Research Foundation
Alzheimer’s Research UK
Medical Research Council
Received: 12 May 2020
Accepted: 14 July 2020
First Online: 31 July 2020
Ethics approval and consent to participate
: All components of the Generation Scotland received ethical approval from the NHS Tayside Committee on Medical Research Ethics (REC Reference Numbers: 05/S1401/89 and 10/S1402/20). All participants provided broad and enduring written informed consent for biomedical research. The Generation Scotland has also been granted Research Tissue Bank status by the East of Scotland Research Ethics Service (REC Reference Number: 15/0040/ES). This study was performed in accordance with the Helsinki declaration.
: Not applicable.
: AMM has received research support from Eli Lilly, Janssen and the Sackler Foundation. AMM has also received speaker fees from Illumina and Janssen. The other authors declare that they have no competing interests.