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Differential DNA methylation by early versus late parenteral nutrition in the PICU: a biological basis for its impact on emotional and behavioral problems documented 4 years later

Crossref DOI link: https://doi.org/10.1186/s13148-021-01124-3

Published Online: 2021-07-27

Published Print: 2021-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Jacobs, An

Güiza, Fabian

Verlinden, Ines

Dulfer, Karolijn

Garcia Guerra, Gonzalo

Joosten, Koen

Verbruggen, Sascha C.

Vanhorebeek, Ilse http://orcid.org/0000-0002-5261-5192
Van den Berghe, Greet
Funding

Funding for this research was provided by:

FP7 Ideas: European Research Council (AdvG-2012-321670)

H2020 European Research Council (AdvG-2017-785809)

Methusalem program of the Flemish government (METH14/06, METH14/06)

Agentschap voor Innovatie door Wetenschap en Technologie (IWT-TBM110685)

Sophia Research Foundation (-)

Stichting Agis Zorginnovatie (-)

Erasmus Trustfonds (-)

European Society for Clinical Nutrition and Metabolism (ESPEN Research grant)
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Text and Data Mining valid from 2021-07-27

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Article History

Received: 21 April 2021

Accepted: 25 June 2021

First Online: 27 July 2021

Declarations

:

: Institutional Review Board approval had been obtained in the three centres participating in the PEPaNIC study (Leuven: ML8052; Rotterdam: NL49708.078; Edmonton: Pro00038098) and the study was performed in accordance with the 1964 Declaration of Helsinki and its amendments. Parents or legal guardians of the children provided written informed consent.

: Not applicable.

: The authors declare that they have no competing interests.

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