Funding for this research was provided by:
Fondazione Bambino Gesù (Vite Coraggiose)
Italian Ministry of Health (RCR-2020-23670068_001, Ricerca Corrente 2021, CCR-2017-23669081, Ricerca Corrente 2020)
Italian Ministry of Research (FOE 2019)
London Health Sciences Molecular Diagnostics Development Fund (EpiSign-CAN)
Genome Canada Genomic Applications Partnership Program Grant (EpiSign-CAN)
Received: 3 June 2021
Accepted: 31 July 2021
First Online: 11 August 2021
: This study was approved by the Ethical Committee of the Ospedale Pediatrico Bambino Gesù (1702 OPBG 2018), and by the Western University Research Ethics Board (REB 106302). DNA specimens from the subjects included in this study were collected following procedures in accordance with the ethical standards of the declaration of Helsinki protocols and approved by the Review Boards of all involved institutions, with signed informed consents from the participating subjects/families.
: Not Applicable.
: The authors declare that they have no competing interests.