Sarnowski, Chloé
Huan, Tianxiao
Ma, Yiyi
Joehanes, Roby
Beiser, Alexa
DeCarli, Charles S.
Heard-Costa, Nancy L.
Levy, Daniel
Lin, Honghuang
Liu, Ching-Ti
Liu, Chunyu
Meigs, James B.
Satizabal, Claudia L.
Florez, Jose C.
Hivert, Marie-France
Dupuis, Josée
De Jager, Philip L.
Bennett, David A.
Seshadri, Sudha
Morrison, Alanna C.
Funding for this research was provided by:
National Institute on Aging (R00 AG066849, R01 AG054076, R01 AG054076, U01 AG068221, R01 AG059727, R01 AG054076)
Alzheimer's Association (2019-AARF-644521)
National Institute of Diabetes and Digestive and Kidney Diseases (U01 DK078616)
National Heart, Lung, and Blood Institute (R01 HL151855, K24 HL157960)
Article History
Received: 17 July 2023
Accepted: 20 October 2023
First Online: 27 October 2023
Declarations
:
: All FHS participants provided written informed consent at each examination. The FHS protocol for blood collection and DNA methylation was approved by the Institutional Review Board of the Boston University Medical Campus. This study has been approved by the UTHealth Institutional Review Board (HSC-SPH-21–0072).ROSMAP parent studies and sub-studies were all approved by an Institutional Review Board of Rush University Medical Center and all participants signed an informed consent, Anatomical Gift Act, and a repository consent to share data and biospecimens.
: Not applicable.
: Dr. Meigs is Academic Associate for Quest Inc. Endocrine R&D. Dr. Florez has received speaking honoraria from AstraZeneca and Novo Nordisk for scientific talks over which he had full control of content. The other authors declare that they have no competing interests. The views expressed in this manuscript are those of the authors and do not necessarily represent the views of the National Heart, Lung, and Blood Institute; the National Institutes of Health; or the US Department of Health and Human Services. This manuscript was not prepared in collaboration with investigators of the Framingham Heart Study and does not necessarily reflect the opinions or views of the Framingham Heart Study, Boston University, or NHLBI.