Funding for this research was provided by:
the National Science and Technology Major Projects of New Drugs (2015ZX09102015)
Strategic Leading Project of China Academy of Sciences (XDA 2040215)
Received: 26 October 2017
Accepted: 30 April 2018
First Online: 19 June 2018
Ethics approval and consent to participate
: The animal treatment, husbandry, and experimental protocols of the present study received the approval of the Tsinghua University Animal Care and Use Committee (reference number 15-LRT1). All animal tests were carried out in accordance with the China Public Health Service Guide for the Care and Use of Laboratory Animals.
: The authors declare that they have no competing interests.
: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.