Funding for this research was provided by:
National Institutes of Health (AG008051, NS073502)
Alzheimer's Association (IIRG-13-283707)
Received: 21 February 2018
Accepted: 10 May 2018
First Online: 18 June 2018
Ethics approval and consent to participate
: For human samples used during the course of this study, all procedures were performed under protocols approved by the Institutional Review Board at New York University Alzheimer’s Disease Center, New York. In all cases, written informed consent for research was obtained from the patient or legal guardian, and the material used had appropriate ethical approval for use in this project. All patient data and samples were coded and handled according to NIH guidelines to protect patient identities. Animal studies performed during the course of this project were approved by the New York University School of Medicine Institutional Animal Care and Use Committee and were consistent with the recommendations of the American Veterinary Association. Mice facilities were under a strict 12-h light/dark cycle. A general examination of the mice was conducted daily during the course of the experiment. Overall observations and any gross abnormalities in overall health, home cage nesting, behavior, grooming, and condition of the fur of the animals was noted. Body weight was measured twice during the study period.
: The authors declare that they have no competing interests.
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