Funding for this research was provided by:
FONDAZIONE ITALO MONZINO
Text and Data Mining valid from 2018-10-12
Received: 15 February 2018
Accepted: 20 September 2018
First Online: 12 October 2018
Ethics approval and consent to participate
: All patients or their relatives gave informed consent for participation in this study, which was approved by the local ethics committee at Istituto di Neurologia, Università di Parma (PC), under the responsibility of Prof. Paolo Caffarra. Animal studies were run in compliance with national laws, regulations, and policies governing the care and use of laboratory animals: Italian Governing Law (D.lgs 26/2014; authorization no. 19/2008-A, issued March 6, 2008, by the Ministry of Health); Mario Negri institutional regulations and policies providing internal authorization for people conducting animal experiments (Quality Management System Certificate UNI EN ISO 9001:2008 registration no. 6121); the National Institutes of Health (NIH) Guide for the Care and Use of Laboratory Animals (2011 edition), and European Union directives and guidelines (EEC Council Directive 2010/63/UE). The Statement of Compliance (Assurance) with the Public Health Service (PHS) Policy on Human Care and Use of Laboratory Animals was recently reviewed (September 9, 2014) and will expire on September 30, 2019 (Animal Welfare Assurance no. A5023-01, DL. vo 116/1992, Gazzetta Ufficiale, Suppl. 40, Feb.18, 1992; Circolare nr. 8, Gazzetta Ufficiale, July 14, 1994) and international laws and policies (EEC Council Directive 86/609, OJL 358, 1, Dec.12, 1987; NIH Guide for the Care and Use of Laboratory Animals 8th edition, 2011).
: Not applicable, because this article does not contain any individual person’s data, images, or videos.
: The authors declare that they have no competing interests.
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