Funding for this research was provided by:
Received: 11 April 2018
Accepted: 4 November 2018
First Online: 28 November 2018
: Animal studies have been validated by an internal ethics committee (see Methods section).Experiments were performed at Sanofi in an AAALAC-accredited facility in full compliance with the standards for the care and use of laboratory animals, according to French and European Community (Directive 2010/63/EU) legislation. All procedures were approved by the local Animal Ethics Committee (CEEA #24) and the French Ministry for Research.
: Not applicable.
: HK and JR are inventors on patent application W02009/065054 describing the murine antibody 13C3 from which the antibodies described in this manuscript are derived. Sanofi hold a license to the derived intellectual property. LK, Neurotar Ltd., performed this work as part of a research contract with Sanofi.
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