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Article History

Received: 29 January 2019

Accepted: 28 April 2019

First Online: 15 May 2019

Ethics approval and consent to participate

: The Medical Ethical Committee of the VU University Medical Center approved the study for all Dutch centers. The South East Scotland Research Ethics Committee approved the study for the Scottish site. All participants and study partners provided written and oral informed consent for the use of their data for research purposes.

: Not applicable

: RJJ, PRL, RV, RAJD, FJJ, EMO, and CWR declare that they have no competing interests. In the past 2 years, JEH has received honoraria and paid consultancy from 23andMe, Abbvie, A2Q, AlzCure, Amgen, Anavex, Aptinyx, Astellas, AstraZeneca, Avraham, Axon, Axovant, Biogen, Boehringer Ingelheim, Bracket, Catenion, Cognition Therapeutics, CRF Health, Curasen, DeNDRoN, Enzymotec, Eisai, Eli Lilly, GfHEu, Heptares, Johnson & Johnson, Kaasa Health, Lysosome Therapeutics, Lundbeck, Merck, MyCognition, Mind Agilis, Neurocog, Neurim, Neuroscios, Neurotrack, Novartis, Nutricia, Pfizer, PriceSpective, Probiodrug, Regeneron, Rodin Therapeutics, Roche, Sanofi, Servier, Shire, and Takeda & vTv Therapeutics. SI received support from the EU/EFPIA Innovative Medicines Initiative Joint Undertaking EPAD grant agreement no. 115736. AA has received speaker fees from Lundbeck. PS has acquired grant support (for the institution) from GE Healthcare and Piramal. In the past 2 years, he has received consultancy/speaker fees (paid to the institution) from Novartis, Probiodrug, Biogen, Roche, and EIP Pharma, LLC. BMT receives grant support from ZonMW. SAMS is supported by grants from JPND and Zon-MW and has provided consultancy services in the past 2 years for Lundbeck. All funds were paid to her institution.

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