Funding for this research was provided by:
National Natural Science Foundation of China (81371223, 81571061)
Liaoning Provincial Key R&D Program (2019020048-JH2/103)
National Major Scientific and Technological Special Project for "Significant New Drugs Development" (2019zx09301102)
Liaoning Revitalization Talents Program (XLYC1808031)
National Natural Sciences Foundation of China (30973519)
Liaoning Revitalization Talents Program (XLYC1902044)
Received: 31 December 2019
Accepted: 7 April 2020
First Online: 24 April 2020
Ethics approval and consent to participate
: This study was carried out in accordance with the recommendations of “the National Institute of Health Guide for the Care and Use of Laboratory Animals” (NIH Publications No. 80-23, revised 1996). The animals were handled in accordance with the guidelines of the Committees of Animal Use and Protection, and all efforts were made to minimize the number of animals used and their suffering. All experimental and animal protocols were approved by the animal studies committees of Dalian Medical University (ethics committee approval permit no. L2013011).
: Not applicable.
: The authors declare that they have no competing interests.