Funding for this research was provided by:
Innovative Medicines Initiative (115952)
Received: 17 November 2020
Accepted: 26 March 2021
First Online: 19 April 2021
: All participants provided written informed consent and the original study was approved by the Institutional Review Board of Washington University School of Medicine.
: Not applicable.
: ILA, FH, LEC, GS, NT, PM, MY, DC, ECM, and PSI all report no existing potential conflicts of interest relevant to this article.NV-T is funded by a post-doctoral grant, Juan de la Cierva Programme (FJC2018-038085-I), Ministry of Science and Innovation– Spanish State Research Agency. All CRG authors acknowledge the support of the Spanish Ministry of Science, Innovation and Universities to the EMBL partnership, the Centro de Excelencia Severo Ochoa, and the CERCA Programme/Generalitat de Catalunya.FB received payment and honoraria from Bayer-Schering Pharma, Sanofi-Aventis, Genzyme, Biogen-Idec, TEVA, Merck-Serono, Novartis, Roche, Jansen Research, IXICO Ltd., GeNeuro, Combinostics, and Apitope Ltd. for consulting; payment from the Serono Symposia Foundation, IXICOLtd, and MedScape for educational presentations; and research support via grants from EU/EFPIA Innovative Medicines Initiative Joint Undertaking (AMYPAD consortium), EuroPOND (H2020), UK MS Society, Dutch MS Society, PICTURE (IMDI-NWO), NIHR UCLH Biomedical Research Centre (BRC), and ECTRIMS-MAGNIMS.JDG has received speaker’s fees from Biogen and Philips. In addition, he holds a “Ramón y Cajal” fellowship (RYC-2013-13054) and has received research support from the EU/EFPIA Innovative Medicines Initiative Joint Undertaking AMYPAD grant agreement n° 115952 and from Ministerio de Ciencia y Universidades (grant agreement RTI2018-102261).BNMvB received research support from ZON-MW, AVID radiopharmaceuticals, CTMM, and Janssen Pharmaceuticals.