Co, Melissa
Mueller, Christoph
Mayston, Rosie
Das-Munshi, Jayati
Prina, Matthew
Funding for this research was provided by:
Economic and Social Research Council (ES/S012567/1)
National Institute for Health Research
Medical Research Council (MR/S028188/1, MR/T037423/1, MR/T038500/1)
Article History
Received: 29 March 2022
Accepted: 5 December 2022
First Online: 29 March 2023
Declarations
:
: CRIS has received ethical approval as an anonymised database for secondary analysis from the Oxford Research Ethics Committee C, reference 18/SC/0372. The CRIS-HES linkage has approval under section 251, granted in July 2011 by the Health Research Authority (HRA) Confidentiality Advisory Group (CAG) (reference: ECC 3-04 (f)/2011) covering the use of patient information without consent. This was applied for and approved to make feasible a large enough sample size to fulfil the medical purpose of CRIS research, maximise representativeness of the sample to a general clinical population, and minimise the risk of de-anonymisation through small cell sizes. Patients are able to opt out of their data being stored in both CRIS and HES databases through local and national opt-outs, which are applied prior to researchers accessing the data.
: Not applicable.
: The authors declare that they have no competing interests.