Funding for this research was provided by:
Biotechnology and Biological Sciences Research Council (BB/P000479/1, BB/M008975/1)
Medical Research Council (G0900625)
Alzheimer's Society (AS-JF-15-008)
The Royal Society (RG130316)
FP7 Ideas: European Research Council (FP7/2007–2013)
Text and Data Mining valid from 2019-02-28
Received: 15 October 2018
Accepted: 18 February 2019
First Online: 28 February 2019
Ethics approval and consent to participate
: All experiments were performed under UK Home Office Project and Personal Licenses in accordance with the Animals (Scientific Procedures) Act 1986, and with the approval of the University of Leeds and Durham University Animal Ethical and Welfare Review Boards.
: Not applicable
: The authors declare that they have no competing interests.
: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.