Funding for this research was provided by:
Canadian Institutes of Health Research (MOP-119541, MOP-142379)
Received: 7 October 2019
Accepted: 18 November 2020
First Online: 7 December 2020
Ethics approval and consent to participate
: This study was approved by the Research Ethics Board at the Hospital for Sick Children in Toronto, Canada (REB #1000007826 and #1000051746). Informed written consent was obtained from all participants.
: Not applicable.
: The authors declare that they have no competing interests.