Clinical trials referenced in this document:
Funding for this research was provided by:
National Institute of Neurological Disorders and Stroke (U54NS092090)
Ambrose Monell Foundation
Received: 2 October 2020
Accepted: 15 December 2020
First Online: 28 January 2021
Ethics approval and consent to participate
: The study was approved by the local institutional review boards of the participating centers, and written informed consent was obtained from all participants or their legal guardians with assent obtained from participants age < 18 years who were deemed able to provide assent.
: Not applicable.
: TWF has received funding or research support from, acted as a consultant to, received travel support from, and/or received a speaker’s honorarium from Quadrant Biosciences, Impel NeuroPharma, F. Hoffmann-La Roche AG Pharmaceuticals, the Cole Family Research Fund, Simons Foundation, Ingalls Foundation, Forest Laboratories, Ecoeos, IntegraGen, Kugona LLC, Shire Development, Bristol-Myers Squibb, Roche Pharma, National Institutes of Health, and the Brain and Behavior Research Foundation and has an investor stake in Autism EYES LLC. JAMA has no competing interests. MS reports grant support from Novartis, Roche, Pfizer, Ipsen, LAM Therapeutics, Astellas, Aucta, Bridgebio, and Quadrant Biosciences. He has served on Scientific Advisory Boards for Sage, Roche, Celgene, Aeovian, Regenxbio, and Takeda.