Funding for this research was provided by:
Ministry of Science and Technology of the People's Republic of China (2014ZX09101042-00, 2013DFA30830)
China Postdoctoral Science Foundation (2014 M 561712)
Received: 6 September 2017
Revised: 3 January 2018
Accepted: 4 January 2018
First Online: 22 January 2018
Ethics approval and consent to participate
: All of the human cells used in this study were obtained from healthy young donors in the West China Hospital (Chengdu, China) after their written informed consent. The study was approved by the Hospital’s Ethics Committee and Research Ethics Advisory Committee (Permit Number 2014SZSLK073). All research involving animals was conducted according to relevant national and international guidelines. The experimental protocols were approved by the Yunnan Province Experimental Animal Management Association and the Experimental Animal Ethic Committee of the Institute (Permit Number SYXK-YN No. 2010-0009), following the guidelines of the US National Institutes of Health. Animal care and treatment complied with the humane 3Rs. All surviving animals were also euthanized at the study endpoint under anesthesia using a pentobarbital-based euthanasia solution.
: Not applicable.
: The authors declare that they have no competing interests.
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