Article History
Received: 13 November 2017
Revised: 5 February 2018
Accepted: 11 February 2018
First Online: 9 March 2018
Ethics approval and consent to participate
: All animal experiments were performed under institutionally approved protocols for the use of animal research at University of Pennsylvania (IACUC# 805478) and Peking University (#LA2012–65).
: Not applicable.
: The authors declare that they have no competing interests.
: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.