Funding for this research was provided by:
National Institute of Dental and Craniofacial Research (5RO1-DE13420-09)
Received: 20 September 2018
Revised: 14 October 2018
Accepted: 5 November 2018
First Online: 21 November 2018
Ethics approval and consent to participate
: The use of human tissues was approved by the Institutional Review Board (IRB) of the University of Pittsburgh, and all animal experiments and procedures were approved by the Institutional Animal Care and Use Committee (IACUC) of the University of Pittsburgh (protocol number:1006937). Research performed at the University of Texas Health Science Center at Houston (UTHealth) was approved by the UTHealth Institutional Biosafety Committee and Animal Welfare Committee approved protocol (AWC-15-0074). The University of Pittsburgh and UTHealth were accredited by the Association For Assessment and Accreditation of Laboratory Animal Care (AAALAC). The use of animals for in vivo study followed the guidelines of the “Basel Declaration” and “ethical guidelines” of the International Council for Laboratory Animal Science (ICLAS).
: Not applicable.
: The authors declare that they have no competing interests.
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