Funding for this research was provided by:
National Institute of Health of United States (R21AR066206)
Received: 22 May 2019
Revised: 31 July 2019
Accepted: 30 September 2019
First Online: 26 November 2019
Ethics approval and consent to participate
: The use of human tissues was approved by the Institutional Review Board (IRB) of the University of Texas Health Science Center at Houston (UTHealth), and all animal experiments and procedures were approved by the Institutional Animal Care and Use Committee (IACUC) of the UTHealth (Protocol number: AWC-15-0072). UTHealth was accredited by Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC). The use of animals for in vivo study followed the guidelines of “Basel Declaration” and “ethical guidelines” of the International Council for Laboratory Animal Science (ICLAS).
: Not applicable.
: The authors declare that they have no competing interests.