Funding for this research was provided by:
Deutsche Forschungsgemeinschaft (363055819 - GRK2415, RO 5102-1-1, WA 1706-11-1, WA1706-8-1)
Interdisziplinäres Zentrum für Klinische Forschung, Universitätsklinikum Aachen (O3-3)
Text and Data Mining valid from 2020-03-05
Received: 4 December 2019
Revised: 10 February 2020
Accepted: 24 February 2020
First Online: 5 March 2020
Ethics approval and consent to participate
: Femoral bone samples for the isolation of MSCs were collected after informed and written consent, and the study was approved by the Ethics Committee of RWTH Aachen University Medical School (EK 252/12).
: Not applicable.
: WW is a cofounder of Cygenia GmbH, which can provide service for epigenetic senescence signatures and Epi-Pluri-Score analysis (ExternalRef removed). RG and JF also contribute to this company. Apart from this, the authors do not declare any conflicts of interest.