Funding for this research was provided by:
Fundação para a Ciência e a Tecnologia (PD/59/2013, PD/BD/113800/2015, IF/00347/2015, CEECIND/00695/2017, IF/00945/2014)
Received: 30 September 2020
Accepted: 14 December 2020
First Online: 15 January 2021
Ethics approval and consent to participate
: All human tissue samples were collected after the patient consent and under a collaboration protocol approved by the ethic committees of the involved institutions. Experimental protocols involving animals were approved by the local animal welfare body and performed according to the applicable national regulations and international animal welfare rules.
: Not applicable
: The authors declare that they have no competing interests.