Funding for this research was provided by:
National Center for Advancing Translational Sciences (CTSA UL1TR001420)
Wake Forest School of Medicine (startup)
National Cancer Institute (P30CA012197)
National Institutes of Health (P30AG021332)
CTSA Translational Therepeutics Accelerator (NCATS UL1TR001873)
Received: 8 January 2019
Accepted: 23 April 2019
First Online: 17 May 2019
Ethics approval and consent to participate
: No human data.All animal experiments were conducted under IACUC approved protocols in compliance with the guidelines for the care and use of research animals established by Wake Forest Medical School Animal Studies Committee.
: Not Applicable
: KKSS and AM have a provisional patent application for the use of the novel ascorbate derivatives in this manuscript as PET radiotracers to image oxidative stress in cancer. The other authors declare that they have no competing interests.
: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.