Funding for this research was provided by:
Received: 5 June 2019
Accepted: 16 July 2019
First Online: 25 July 2019
Ethics approval and consent to participate
: Written informed consent was obtained from the patient in accordance with paragraph 37 of the updated Declaration of Helsinki, “Unproven Interventions in Clinical Practice,” and in accordance with the German Medical Products Act AMG §13 2b. All applicable international, national, and/or institutional guidelines for the care and use of animals were followed. In particular, all animal experiments were carried out according to the guidelines of Swiss Regulations for Animal Welfare. The preclinical studies have been ethically approved by the Cantonal Committee of Animal Experimentation and permitted by the responsible cantonal authorities.
: Written informed consent was obtained by the patient for collection and storage of his data in the institutional electronic databank, as well as the publication of the said data.
: The authors declare that they have no competing interests.